Sunday, February 27, 2011
Super-SILAC Technology for Quantitative Proteomics in Neoplasms
A group of investigators under Dr. Matthias Mann at Max Planck Institute of Biochemistry in Martinsried, Germany is working on an interesting quantitative proteomics technology that might offer a new way to analyze cell proteins in a range of disorders, such as cancer and autoimmune diseases. Called super-SILAC (stable-isotope labeling by amino acids in cell culture), the method generates thousands of isotopically labeled peptides in unique amounts to serve as "internal standards for mass spectrometry-based analysis."
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