Exploring science is typically characterized by a lot of puzzles, frustrations or even failures. This weblog is mainly intended to record my working, thinking and knowledge acquisitions. I expect that some reflection would refresh my mind from time to time, and motivate me to move further, and hopefully give me a better view about even changing the landscape of bioinformatics. You are welcome to leave some comments, good or bad, but hopefully something constructive. Enjoy your surfing!
Friday, December 10, 2010
FAIMS
Field Asymmetric Ion Mobility (FAIMS) - Mass Spectrometry
Field Asymmetric Ion Mobility Spectrometer (FAIMS) is a high speed, gas phase ion separation technique. When interfaced to a Mass Spectrometer, the FAIMS chip provides an additional separation stage, making it suitable for a applications ranging from drug development to proteomics.
The FAIMS ion filter is orthogonal to both LC and MS, so has the potential to separate analytes that are difficult to distinguish using only LC-MS. In some cases, the FAIMS stage can replace the LC and associated sample preparation steps.
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